Tactical Planning of Three-Level Supply Chain considering Sanction Disruption and Shelf Life: A case Study of ATRA Drug Supply Chain

Document Type : Research Paper


1 MSc, Economic and Social Systems Engineering, Iran University of Science and Technology

2 Associate Prof, Faculty of Industrial Technology, Iran University of Science and Technology, Tehran, Iran

3 Associate Prof, Faculty of Economic and Social Systems Engineering, Iran University of Science and Technology, Tehran, Iran

4 Associate Prof, Faculty of Economic and Social Systems Engineering, Iran University of Science and Technology,Tehran, Iran


In the last two decades due to globalization of supply chain, enormous changes occurred in chains. Leaders in this field, always facing new risks and disorders that should prepare themselves to deal with them. In the recent years, sanctions as one of the most serious risks have damaged the supply chains. However, in the research related to global supply chains, modeling of disruption has been neglected. The purpose of this study was the modeling of drug supply chain at the tactical level in terms of sanction impairing. Physical and financial flow and their disruption in the term of sanction have been modeled simultaneously. To complete the financial flow, financial statements have also been modeled. One of the newest approaches named Robust Possibilistic Programming has been used for the modeling of the uncertainty of the problem. The model has been implemented on a drug organization called Atra and the results have been analyzed and validated by the optimization software Gams. The results show a robust and resistant system in the case of sanction disruption that without violating the constraints of the problem shows the appropriate measures to deal with the problem.


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